Table 1.
Comparative performance of ELISA and the luciferase immunoprecipitation systems (LIPS) method for the diagnosis of Strongyloides stercoralis infection.
| Test | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| ELISA | ||||
| IgG NIE | 97 | 95 | 88 | 99 |
| IgG4 NIE | 45 | 100 | 100 | 64 |
| LIPS assay | ||||
| Ruc-NIE | ||||
| IgG | 97 | 100 | 100 | 99 |
| IgG4 | 87 | 100 | 100 | 90 |
| Ruc-SsIR | 97 | 97 | 94 | 99 |
| Ruc-NIE/Ruc-SsIR | 100 | 100 | 100 | 100 |
NOTE. Data are percentages. NPV, negative predictive value; PPV, positive predictive value; Ruc, Renilla luciferase; SsIR, S. stercoralis immunoreactive antigen.