Table 5.
The haplogroup defining SNP (A12308G) and the T195C allele in D-Loop region were tested in a post hoc analysis using a Cochran–Mantel–Haenszel (CMH) test for repeated 2 × 2 tests of independence.
mtDNA allele |
Group |
|||
---|---|---|---|---|
12308 | 195 | Control (n) | SZ (n) | BD (n) |
A | T | 2600 | 761 | 629 |
C | 417 | 82 | 81 | |
G | T | 701 | 193 | 180 |
C | 168 | 37 | 40 | |
Total N | 3886 | 1073 | 930 | |
CMH | 10.62 | 2.69 | ||
df | 2 | 2 | ||
CMH p-value | 0.0011 | 0.1007 |
The results for SZ remained significant (p = 0.0011) while combined results of SZ and BD were also significant (not shown, p = 0.001).