Fig. 10.

Airway acid-induced endothelial TF, vWf, and P-selectin expressions are inhibited in WT lungs perfused with gp91phox^−/− blood. Pulmonary vascular cells were freshly isolated from WT untreated lungs perfused with WT blood or from WT lungs that were acid instilled and either perfused with WT blood or blood from gp91phox^−/− mice. Dot plots of single experiments show expression (% of total). The x and y ordinates (gray lines) indicate nonimmune isotype specific IgG label. A: top row, TF and vWf and bottom row, vWf, and P-selectin. B: group data, n = 4 mice each bar. Data are means ± SE. *P < 0.05 compared with bar on left.