Fig. 11.

Airway acid-induced TF, vWf, and P-selectin expressions are inhibited on platelets of gp91phox^−/− mouse. Control, untreated. Platelets were isolated from WT and gp91phox^−/− blood in untreated or acid instillation conditions. Dot plots of single experiments show expression (% of total). The x and y ordinates (gray lines) indicate nonimmune isotype specific IgG label. A: TF and vWf (top row), and vWf and P-selectin (bottom row). B: group data show paired responses on platelets from WT and gp91phox^−/−, respectively, n = 4 mice each bar. Data are means ± SE. *P < 0.05 compared with bar on left. #P < 0.05 compared with untreated control.