Fig. 7.

Airway acid induces expression of the platelet proteins, CD41 and CD42b on CD45− cells expressing VE-cadherin. Pulmonary vascular cells were freshly isolated from mice subjected to intranasal saline or acid instillation. Dot plots from single experiments show expression (% of total) in isolated CD45− cells. The x and y ordinates (gray lines) indicate nonimmune isotype specific IgG label. A: CD41 and VE-cadherin. B: CD42b and VE-cadherin. C: group data for VE-cadherin+/CD41+ cells. D: group data for and VE-cadherin+/CD42b+ cells. Means ± SE, n = 4 mice each bar, *P < 0.05 compared with bar on left.