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Serotonylation of FN in serum of patients with PAH. s-FN/FN was determined in sera from patients with PAH and compared with that from controls. A: representative electrophoretic blots of s-FN and FN in serum from 5 PAH patients and 3 controls. B: comparisons for all patients studied; we show mean s-FN/FN of patients with PAH (n = 19) vs. controls (n = 25). Mean value for PAH = 0.3 ± 0.18 vs. 0.05 ± 0.07 for controls; P < 0.001.
