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Number of 15-μm microspheres found in the kidneys of intact, spontaneously breathing rats exposed to normoxia or hypoxia
| Group 1: Normoxia (FiO2 = 0.21) | Group 2: Hypoxia (FiO2 = 0.12) | ||
|---|---|---|---|
| Rat 1 | 0 | Rat 1 | 11 |
| Rat 2 | 0 | Rat 2 | 204 |
| Rat 3 | 0 | Rat 3 | 5,004 |
| Rat 4 | 2 | Rat 4 | 380 |
| Rat 5 | 0 | Rat 5 | 859 |
| Rat 6 | 254 | ||
| Mean ± SD | 0 ± 1 | Mean ± SD | 1,119 ± 1,925* |
Exposure to FiO2 = 0.08 increased the number of microspheres found in the kidney compared with exposure to FiO2 = 0.21 (* P = 0.008).
