Table 12F: Level of Evidence of Included Studies on Impact of Previous Fracture on Risk of Future Fractures *.
| Type of Study (Design) | Level of Evidence |
No. of Eligible Studies |
|---|---|---|
| Large RCT, Systematic reviews of RCTs | 1 | |
| Large RCT, unpublished but reported to an international scientific meeting | 1(g) | |
| Small RCT | 2 | |
| Small RCT unpublished but reported to an international scientific meeting | 2(g) | |
| Non-RCT with contemporaneous controls | 3 a | |
| Non-RCT with historical control | 3b | |
| Non-RCT unpublished but reported to an international scientific meeting | 3(g) | |
| Surveillance (database or register) | 4a | |
| Pooled analysis of observational studies | 4 | 3 |
| Case series, multisite (Population-based observational) | 4b | 13 |
| Case series, single-site | 4c | |
| Case series unpublished but presented to an international scientific meeting | 4(g) | |
| Total | 16 | |
*
g refers to grey literature; RCT, randomized controlled trial.