Table 15: Interval Between Baseline BMD and Treatment Threshold Based on Baseline BMD, Rate of Bone Loss, and Risks of Fractures.
| Age | Sex | Other risk factors for fractures * |
Baseline BMD (gm/cm2) † |
Rate of BMD loss (% per year) |
BMD Threshold to initiate treatment (gm/cm2) † |
Time interval to reach threshold to initiate treatment yrs. |
|---|---|---|---|---|---|---|
| >65 yrs | Women | None | T-score =0 BMD = 0.849 |
3 | T-score = -2.5 BMD = 0.572 |
12 |
| >65 | Women | None | T-score up to –1 BMD = 0.738) |
1 | T-score = –2.5 BMD = 0.572 |
24 |
| >65 | Women | None | T-score up to –1 (0.738) | 2 | T-score = –2.5 BMD = 0.572 |
11 |
| >65 | Women | None | T-score up to –1 (0.738) | 3 | T-score = –2.5 BMD = 0.572 |
8 |
| >65 | Women | None | T-score up to –1 BMD = 0.738) |
1 | T-score = –2 BMD = 0.627 |
16 |
| >65 | Women | None | T-score up to –1 (0.738) | 2 | T-score = –2 BMD = 0.627 |
7 |
| >65 | Women | None | T-score up to –1 (0.738) | 3 | T-score = –2 BMD = 0.627 |
5 |
| >65 yrs | Women | None | T-score –1.5 0.683 osteopenic |
3 | T-score = –2.5 BMD = 0.572 |
5 |
| >65 yrs | Women | None | T-score–1.5 0.683 osteopenic |
3 | T-score = –2 BMD = 0.627 |
2 |
| Women | Yes * | T-score = -1 BMD>0.738 |
1 | T-score =– 1.5 BMD = 0.683 |
6 | |
| Women | Yes * | T-score = -1 BMD>0.738 |
2 | T-score = –1.5 BMD = 0.683 |
3 | |
| Women | Yes * | T-score = -1 BMD>0.738 |
3 | T-score =– 1.5 BMD = 0.683 |
2 | |
| Any age | Women & men | Glucocortic oids therapy | Any BMD | Regardless of BMD | Guidelines Every 6 to 12 months |
*
History of fracture & advanced age, condition or medication associated with rapid bone loss, and/or history of fracture in first-degree relative
†
BMD in gm/cm2 based on femoral neck for Caucasian women (Hologic densitometers)