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. 2006 Nov 1;6(20):1–180.

Table 29: Bone-Mass Related High-Risk Factors for Fractures*.

High-risk factors High-risk factors
Meta-analysis RR (95% CI) Range of reported RR
Aging (>70-80 yrs) 1.27 (1.22–1.77) for 10 yr increase in age Primary hyperparathyroidism 2.56–3.49
Low body weight 2.35 (1.7–3.14) low vs. high body weight Diabetes Mellitus Type I 2.91–3.79
Weight loss 1.3 (1.09–1.55) for 10 kg weight loss Anorexia Nervosa No data
Reduced physical inactivity Risk interval 1.18–7.1 Gastrectomy 1.83 (risk interval)
Corticosteroids 1.78(1.37–2.32)
2.15 (1.59–2.91)
Pernicious anemia 2.9–3.8
Anticonvulsants 2.64 (1.82–3.82) Prior Osteoporotic fractures 1.35–21.5
*

CI refers to confidence interval; RR, relative risk;

for femoral neck fractures

Source: Espallargues M, Sampietro-Colom L, Estrada MD, Sola M, Del Rio L, Setoain J et al. Identifying bone-mass-related risk factors for fracture to guide bone densitometry measurements: a systematic review of the literature. Osteoporos Int 2001; 12(10): 811-822