Table 29: Bone-Mass Related High-Risk Factors for Fractures*.
High-risk factors | High-risk factors | ||
---|---|---|---|
Meta-analysis RR (95% CI) | Range of reported RR | ||
Aging (>70-80 yrs) | 1.27 (1.22–1.77) for 10 yr increase in age | Primary hyperparathyroidism | 2.56–3.49 |
Low body weight | 2.35 (1.7–3.14) low vs. high body weight | Diabetes Mellitus Type I | 2.91–3.79 |
Weight loss | 1.3 (1.09–1.55) for 10 kg weight loss | Anorexia Nervosa | No data |
Reduced physical inactivity | Risk interval 1.18–7.1 | Gastrectomy | 1.83 (risk interval) |
Corticosteroids | 1.78(1.37–2.32) 2.15 (1.59–2.91) |
Pernicious anemia | 2.9–3.8 |
Anticonvulsants | 2.64 (1.82–3.82) † | Prior Osteoporotic fractures | 1.35–21.5 |
CI refers to confidence interval; RR, relative risk;
for femoral neck fractures
Source: Espallargues M, Sampietro-Colom L, Estrada MD, Sola M, Del Rio L, Setoain J et al. Identifying bone-mass-related risk factors for fracture to guide bone densitometry measurements: a systematic review of the literature. Osteoporos Int 2001; 12(10): 811-822