| Viborg | MASS | Chichester Women | Chichester Men | Perth | Meta-analysis Fixed-Effects Model Men 65+ |
|||
|---|---|---|---|---|---|---|---|---|
| Study, year | Lindholt et al., 2005 (13) | Ashton et al., 2002 (17) | Scott et al., 1995 (16) | Scott et al., 1995 (16) | Norman et al., 2004 (15) | Medical Advisory Secretariat, 2005 | ||
| Randomized | 12,639 | 67,800 | 9,342 | 6,433 | 41,000 | |||
| Invited to screening, no. | 6,333 | 33,839 | 4,682 | 3,205 | 19,352 | |||
| Accepted screening, no. | 4,852 | 27,147 | 3,052 | 2,342 | 63% | |||
| Screened, % | 76.6 | 80 | 65 | 73 | 63 | 72 | ||
| AAAs in screened, no. (%) | 191 (4.0) | 1333 (4.9) | 40 (1.3) | 178 (7.6) | 875 (7.2) | 5.5 | ||
| Uninvited controls, no. | 6,319 | 33,961 | 4,660 | 3,228 | 19,352 | |||
| Duration of follow-up, yrs | 5.75 | 2.9–5.2 | 5 | 5 | 2.5 | |||
| AAA-specific mortality | ||||||||
| Invited, no. (%) | 6 (0.09) | 65 (0.19) | 2 (0.04) | 10 (0.31) | 18 (0.09) | |||
| Controls, no. (%) | 19 (0.30) | 113 (0.33) | 2 (0.04) | 17 (0.36) | 25 (0.13) | |||
| OR (95% CI) | 0.31 (0.13–0.79) | 0.58 (0.42–0.78) | 1.00 (0.14–7.07) | 0.59 (0.27–1.29) | 0.72 (0.39–1.32) | 0.57 (0.45–0.74) | ||
| All-cause mortality | ||||||||
| Invited, no. (%) | 939 (0.15) | 3750 (11.1) | 503 (10.7) | 532 (16.6) | 1976 (10.2) | |||
| Controls, no. (%) | 1019 (0.16) | 3855 (11.4) | 476 (10.2) | 508 (15.7) | 2020 (10.4) | |||
| OR (95% CI) | 0.90 (0.82–0.99) | 0.97 (0.93–1.02) | 1.05 (0.92–1.19) | 1.07 (0.93–1.22) | 0.98 (0.91–1.04) | 0.97 (0.93–1.01) | ||
| Emergency Repair | ||||||||
| Invited, no. (%) | 6 (0.09) | 27 (0.05) | 1 (0.02) | 3 (0.09) | 9 (0.05) | |||
| Controls, no. (%) | 30 (0.47) | 54 (0.04) | 1 (0.01) | 8 (0.24) | 8 (0.04) | |||
| OR (95% CI) | 0.20 (0.08–0.48) | 0.50 (0.32–0.80) | 1.00 (0.06–15.93) | 0.38 (0.10–1.42) | 1.13 (0.43–2.92) | 0.46 (0.24–0.88) | ||
| Elective Repair | ||||||||
| Invited, no. (%) | 50 (0.79) | 332 (0.55) | 4 (0.08) | 28 (0.87) | 107 (0.55) | |||
| Controls, no. (%) | 14 (0.22) | 92 (0.28) | 2 (0.04) | 5 (0.15) | 54 (0.28) | |||
| OR (95% CI) | 3.58 (1.98–6.49) | 3.65 (2.89–4.65) | 1.99 (0.36–10.88) | 5.62 2.14–14.73) | 2.02 (1.46–2.80) | 3.18 (2.11–4.79) | ||
| AAA Rupture | ||||||||
| Invited, no. (%) | 4 (0.10) | 65 (0.17) | 3 (0.06) | 8 (0.25) | 33 (0.17) | |||
| Controls, no. (%) | 20 (0.30) | 134 (0.20) | 2 (0.04) | 20 (0.62) | 38 (0.20) | |||
| OR (95% CI) | 0.20 (0.07–0.58) | 0.50 (0.37–0.68) | 1.49 (0.25–8.94) | 0.40 (0.18–0.91) | 0.87 (0.54–1.38) | 0.50 (0.31–0.80) | ||
| Operative Mortality | ||||||||
| Elective repair, % | 6 | 6 | 0 | 0 | 4.3 | 6 | ||
| Emergency repair, % | 39 | 37 | 33 | 25 | 50 | 37 | ||
*
AAA indicates abdominal aortic aneurysm; CI, confidence interval; OR, odds ratio.