Table 14: Myopia and Risk of Prevalent POAG by Multivariate Analysis.
Study | Age (years) Mean (SD)[Range] | OR (95% CI) | Definition of Myopia (Spherical Equivalent, S.E.) |
Dose Response Effect Found? |
---|---|---|---|---|
Chennai Glaucoma Study (36) | 53.8(10.7) | *0.68 (0.40-1.17) | S.E. worse than -0.5 D in phakic eye | Not assessed |
Aravind Comprehensive Eye Survey (5) | Median:51.0 [40-90] |
†Mild:2.9 (1.3-6.9) †Moderate:2.1 (1.0-4.6) †Severe3.9 (1.6-9.5) |
S.E. worse than -0.5D in either phakic eye No definitions of mild, moderate or severe reported in study. | No |
Beaver Dam Eye Study (45) |
60.6(11.3) |
‡1.6 (1.1, 2.4) (2 eyes) ‡1.6 (0.9-2.6) (right eyes only) |
S.E. of -1.00D or worse | No |
Blue Mountains Eye Study(38) |
Males: 75.9 [49-97] Females: 65.9 [52-96] |
§2.1 (1.2-3.8) ||2.3 (1.3-4.1) |
S.E. of -1.00D or worse | Yes as assessed in people ≥ 60 years of age |
||¶2.3(1.3-4.1) | Low: S.E ≥-1.00 to < -3.0 D | |||
||¶3.3(1.7-6.4) | Moderate to High: S.E. ≥ -3.00 D |
Adjusted for age, gender, IOP, central corneal thickness and hypertension
Adjusted for age, gender, diabetes, hypertension, pseudoexfoliation, myopia
Adjusted for age, gender, education, hypertension, diabetes
Age and gender adjusted
Adjusted for gender, age, glaucoma family history, diabetes, hypertension, history of typical migraine, steroid use, and presence of pseudoexfoliation.
Low, and moderate to severe Myopia for people 60+ years of age. Insufficient data for persons less than 60 years of age to include in analyses.