| High: | ⊕⊕⊕⊕ Further research is very unlikely to change our confidence in the estimate of effect. | |
| Moderate: | ⊕⊕⊕Ο Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. | |
| Low: | ⊕⊕ΟΟ Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. | |
| Very low: | ⊕ΟΟΟ Any estimate of effect is very uncertain. |
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