Study	Enrolment & assignment	Spectrum	Blinding – patient & operator	Interpretation of CAG, IVUS & clinical outcomes	Document ary IVUS in Angio group	Statistical Power	ITT
Park 2001 (32)	Prospective non-randomized controlled study with consecutive patients IVUS @ discretion of operator Some had atherectomy before stenting	Only patients with symptomatic unprotected left main coronary artery stenosis	No	IVUS & QCA by Computer software QCA by two independent angiographers No blinding mentioned Angiographic follow-up done: IVUS 59/77 Angio 41/50	No	Not stated	No
Agostoni 2005 (33)	Prospective non-randomized observational studies	Only patients with symptomatic unprotected left main coronary artery stenosis	No	All analysis performed on line using computer software No off-line analysis mentioned	No	Not stated	No clear

Angio or QCA quantitative coronary angiography; IVUS intravascular ultrasound