| Study | Inclusion Criteria | Exclusion Criteria |
|---|---|---|
| Gaster 2001 (28) | Male patients referred for PCI of a de novo lesion on a native coronary artery | Restenotic lesion, SVG Patients in whom follow-up was deemed unlikely Acute MI<3 months before PCI Unstable angina <1month of PCI Left bundle branch block Atrial fibrillation Elevated level of serum creatinine>200 umol/l Thyrotoxicosis Polycythemia. Total occlusion or unobtainable preprocedure IVUS pullback. |
| SIPs 2000 (25) | Patients undergoing elective or urgent PTCA or primary stenting in vessels of diameter between 2.2mm to 4.6mm |
Chronic total occlusion Lesions in saphenous vein grafts>4.6mm |
| OPTICUS 2001 (21) | Angina or documented ischemia Lesion length </=25mm |
Contraindication to antiplatelet therapy Acute angina at rest Complete akinesia in myocardium supplied by target artery Significant left main lesion, bifurcation lesion, & involvement of a side branch>/=2 mm in diameter with ostial stenosis |
| RESIST 1998(22) 2000 (23) | Single<20mm long stent deployment Balloon/artery ratio for stent placement between 1.0 &1.2 Balloon inflation pressure >12 atmospheres Optimal angiographic results after stent implantation without dissection or residual stenosis >20% on QCA |
Vessel diameter <3.0 mm by visual QCA Coronary lesion >12mm in length Previous CABG Contraindication to antiplatelet therapy Treatment of acute or chronic total occlusion Saphenous vein graft stenosis Acute coronary syndrome <7 days. |
| TULIP 2003 (26) | Consecutive patients referred for elective PCI De novo, nonostial stenosis >/=20mm long in a native coronary artery Reference diameter allowed implantation of >/=3mm stent No involvement of significant side branches (diameter>/=2.0mm) |
MI<2weeks Total occlusion Contraindication for combined antiplatelet therapy with ASA &ticlopidine |
| AVID 1997(31) 2000 (27) (Abstract) |
Low risk for complications who were undergoing elective stent placement in vessels>2.5mm in diameter Successful stent deployment & underwent IVUS |
Vessel<2.5mm |
| Park 2001 (32) | Consecutive patients with symptomatic left main coronary artery diseaseor documented myocardial infarction & angiographic evidence of ≥50% diameter stenosis of the LMCA. Excluded: contraindications | Contraindication to antiplatelet or anticoagulation therapy Left ventricular dysfunction (ejection fraction >40%) |
| Agostoni 2005 (33) | Patients undergoing elective PCI using drug-eluting stents for symptomatic CAD (stenosis >50%) by visual estimation in unprotected left main coronary artery | Acute MI Cardiogenic shock undergoing emergency PCI Protected left main (>/=1 patent bypass graft on the left coronary artery |
Angio or QCA quantitative coronary angiography; PCI percutaneous coronary intervention; PTCA percutaneous transluminal coronary interventions; LMCA left main coronary artery; SVG saphenous vein graft; umol micromole; I litre