Figure 6.

Akt2 promotes cell survival via IKKε. (A) MDA-MB-231 cells were transfected with Akt2, IKKε, or nontargeting siRNA, and a clonogenic assay was performed, as detailed in the Materials and Methods. (B) Quantification of the number of colonies as determined by the clonogenic assay in MDA-MB-231 and MDA-MB-231/Akt2 cells transfected with control nontargeting or IKKε siRNA. The results are representative of 3 independent experiments. **P < 0.01 and ***P < 0.005, using paired Student t test.