FIG. 2.

Transcript was activated under high glucose conditions. A: Kcnj15, Kcnj11, Glut2, and insulin mRNA expression levels in cultured INS1 cells. Each value was normalized to the value expressed in 5 mmol/L glucose. Values are mean ± SEM (n = 5). B: Kcnj15 and actin protein levels in lysates of cultured INS1 cells in 5 and 25 mmol/L glucose (n = 4). C: Activation of human KCNJ15 gene transcription in response to different glucose concentrations (5, 25, 45, or 65 mmol/L). HEK293 cells were cultured for 72 h (n = 6).