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. 2011 Dec 5;590(Pt 3):421–432. doi: 10.1113/jphysiol.2011.220681

Figure 2. Schematic diagram of Gli transcription factors.

Figure 2

Gli1, Gli2 and Gli3 are zinc finger homologues of Drosophila Cubitus interruptus (Ci). The 4 transcription factors are aligned to demonstrate the homology between the various isoforms. Various functional domains of these proteins are indicated. Znf, zinc finger domain; TAD, transcription activation domain; Rep, repressor domain; SuFu BS, suppressor of fused binding site; PC, phosphorylation cluster; *protein kinase A phosphorylation site; cleavage domain: site of cleavage by proteasome. Modified from Hui & Angers, 2011 with permission.