Figure 3. Salmonella containing vacuoles (SCVs) are located at the minus ends of microtubules due to trafficking via dynein, which is recruited to the SCV by the effector SseF.

In contrast SifA through its interaction with SKIP inhibits the recruitment of kinesin, the plus end motor, preventing movement toward the cell periphery. Several effector proteins, SifA, SseF and SseG, also alter host cell trafficking toward the SCV.