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. 2011 Dec 12;590(Pt 3):631–646. doi: 10.1113/jphysiol.2011.224477

Figure 5. Percentage maximal change in spontaneous FR of identified gastric-DMN neurones occurring within 2 min following 100 or 160 pmol i.v. injections of CCK8 or 58 (or 3.3 μl i.v. saline) in either fed or fasted animals.

Figure 5

Comparable numbers of identified gastric-DMN neurones were sensitive to either CCK8 (29 neurones sensitive/32 neurones identified) or CCK58 (26 neurones sensitive/28 neurones identified). Two-way analysis of variance (metabolic state versus doses of CCK) revealed that there was no interaction between metabolic state of the animal or CCK doses. There was a main effect of CCK on spontaneous DMN firing rate (F4,63= 19.61; P < 0.0001) that is exclusively attributable to CCK8. Note, there was no main effect of metabolic state (F4,63= 0.13; P= 0.72).