Table 2.
Detection of brain metastasis in patients from Cohort 2
| Variable | Brain Metastasis as Isolated First Visceral Site | Visceral Metastasis: Extracranial and Brain |
|---|---|---|
| (n = 34) | (n = 83) | |
| Presentation | ||
| Asymptomatic | 10 (29.4%) | 44 (53.0%) |
| Symptomatica | 24 (70.6%) | 30 (36.1%) |
| Altered mental status/cognitive impairment | 6 | 9 |
| Headache | 9 | 7 |
| Nausea/vomiting | 3 | 3 |
| Seizure | 2 | 1 |
| Vision disorder | 2 | 3 |
| Speech disorder | 2 | 5 |
| Balance disorder | 6 | 7 |
| Weakness | 7 | 5 |
| Paresthesias | 2 | 2 |
| Focal neurology | 1 | 4 |
| Unknown | 0 (0.0%) | 9 (10.8%) |
| Basis of brain metastasis diagnosis | ||
| Clinical | 20 (58.8%) | 70 (84.3%) |
| Histologic | 14 (41.2%) | 13 (15.7%) |
aPatients may have presented with more than one symptom.