Table 1.
Strain symbol | Genealogical categorya | 25 mM NaCl preference (%), strain meanb | 75 mM NaCl preference (%), strain meanb | 75 mM NaCl preference (%), strain meanc | Amiloride sensitivityd | NaCl taste threshold (mM), strain mean ± SEMe |
129P3/J | Castle's | 67f | 70f | 60 | Noh i | 30 ± 9 |
A/J | Castle's | 53 | 62 | 56 | Yesj | 30 ± 9 |
BALB/cByJ | Castle's | 68 | 73 | 69 | Noi k m | 7 ± 2 |
C3H/HeJ | Castle's | 59 | 46 | 21 | Yesk n | 13 ± 5 |
C57BL/6ByJ | C57-related | 61g | 62g | 60g | Yesh i j k o | 7 ± 2 |
C57BL/6J | C57-related | 61 | 62 | 60 | Yesh i j k | 5 ± 2 |
CBA/J | Castle's | 48 | 43 | 28 | Yesl | 18 ± 6 |
CE/J | Other | 59 | 70 | 70 | 3 ± 1 | |
DBA/2J | Castle's | 50 | 56 | 51 | Nok p | 9 ± 6 |
FVB/NJ | Swiss | 65 | 79 | 75 | 13 ± 6 | |
NZB/BlNJ | Castle's | 58 | 63 | 63 | Yesl | 5 ± 1 |
PWK/PhJ | Wild-derived | 57 | 68 | 16 ± 3 | ||
SJL/J | Swiss | 61 | 67 | 70 | 6 ± 3 |
If different substrains were used in our current study and in a cited study, this is explained in the footnotes. Only 25 and 75 mM NaCl preference scores are shown to illustrate strain variation; preference scores for other concentrations are accessible on the Monell Mouse Taste Phenotyping Project web site (Tordoff and Bachmanov) and the Mouse Phenome Database (http://phenome.jax.org/). SEM, standard error of the mean.
Based on a genealogy chart of inbred strains (Beck et al. 2000).
The preference scores from Tordoff et al. (2007).
The preference scores from Bachmanov, Beauchamp, et al. (2002).
Ability of amiloride to suppress responses to NaCl in the chorda tympani gustatory nerve.
This study.
The data for a related substrain, 129S1/SvImJ.
The data for a related substrain, C57BL/6J.
The data from Gannon and Contreras (1995).
The data from Ninomiya et al. (1996).
The data from (Cherukuri and McCaughey, unpublished data).
The data from Ninomiya et al. (1989).
The data from Ninomiya et al. (1998).
The data for a related substrain, BALB/cCrSlc (Ninomiya et al. 1989; Ninomiya et al. 1996).
The data for a related substrain, C3H/HeSlc (Ninomiya et al. 1989).
The data for related substrains, C57BL/6CrSlc (Ninomiya et al. 1989; Ninomiya et al. 1996), or C57BL/6J (Gannon and Contreras 1995; Cherukuri and McCaughey, unpublished data).
The data for a related substrain, DBA/2CrSlc (Ninomiya et al. 1989).