Table 4.

Post-index utilization of CD-related health care services

Services	Adherent cohort (MPR ≥ 80%), n = 344	Nonadherent cohort (MPR < 80%), n = 104	P value
Pharmacy services
Infliximab
Patients with at least one claim, n (%)	344 (100)	104 (100)
Claims
Mean (SD)	8.06 (0.93)	4.99 (1.00)
Median	8	5	<0.001
Immunomodulators
Patients with at least one claim, n (%)	158 (46)	46 (44)	0.76
Claims
Mean (SD)	6.87 (3.85)	5.80 (3.76)
Median	7	5	0.08
5-aminosalicylates
Patients with at least one claim, n (%)	112 (33)	33 (32)	0.87
Claims
Mean (SD)	5.26 (3.60)	4.45 (2.87)
Median	4	4	0.35
Corticosteroids
Patients with at least one claim, n (%)	135 (39)	45 (43)	0.46
Claims
Mean (SD)	3.02 (2.63)	4.07 (3.58)
Median	2	2	0.12
Other pharmacy services
Patients with at least one claim, n (%)	254 (74)	79 (76)	0.66
Claims
Mean (SD)	9.08 (6.09)	8.25 (6.60)
Median	8	6	0.10
Outpatient services
Emergency room visits
Patients with at least one claim, n (%)	42 (12)	19 (18)	0.11
Claims
Mean (SD)	1.52 (0.83)	1.26 (0.56)
Median	1	1	0.24
Laboratory and pathology
Patients with at least one claim, n (%)	277 (81)	87 (84)	0.47
Claims
Mean (SD)	14.86 (18.10)	15.53 (17.97)
Median	10	11	0.42
Radiology
Patients with at least one claim, n (%)	99 (29)	35 (34)	0.34
Claims
Mean (SD)	2.21 (1.66)	3.51 (2.64)
Median	2	3	0.004
Physician office visits
Patients with at least one claim, n (%)	314 (91)	98 (94)	0.33
Claims
Mean (SD)	6.49 (4.77)	6.40 (5.87)
Median	6	5	0.69
Surgical services
Patients with at least one claim, n (%)	96 (28)	37 (36)	0.13
Claims
Mean (SD)	2.05 (2.02)	2.03 (1.46)
Median	1	1	0.38
Ancillary/all other outpatient services
Patients with at least one claim, n (%)	336 (98)	102 (98)	0.81
Claims
Mean (SD)	25.38 (14.30)	19.98 (13.91)
Median	22	18	<0.001

Abbreviations: CD, Crohn’s disease; MPR, medication possession ratio; SD, standard deviation.