Table 4.
Adjusted logistic regression analysis for association with nonadherence in order to measure the effect of single drug classes
| NNRTI OR (95% CI) |
STR OR (95% CI) |
|
|---|---|---|
| Male gender | 0.90 (0.50–1.64) | 0.88 (0.47–1.60) |
| Age (by year) | 0.96 (0.94–0.99) | 0.96 (0.93–0.99) |
| CDC C3 | 1.16 (0.67–2.04) | 1.14 (0.65–2.01) |
| CD4 (by 50/μL ) | 0,96 (0.92–1.00) | 0.96 (0.92–1.00) |
| Log10 HIV-RNA | 1.66 (1.08–2.57) | 1.69 (1.09–2.61) |
| Years of therapy (each) | 1.07 (1.02–1.12) | 1.07 (1.02–1.12) |
| OD regimen (vs BID) | 1.23 (0.74–2.05) | 1.60 (0.91–2.82) |
| NNRTI Class | 0.56 (0.34–0.94) | |
| STR | 0.45 (0.22–0.42) |
Abbreviations: STR, single tablet regimen: tenofovir/emtricitabine/efavirenz; OD, once-daily; BID, twice daily; NNRTI, nonnucleoside reverse transcriptase inhibitor; CDC, Centers for Disease Control and Prevention.