. Author manuscript; available in PMC: 2013 Mar 1.

Published in final edited form as: J Mol Med (Berl). 2012 Feb 24;90(3):233–244. doi: 10.1007/s00109-012-0878-z

Table 2.

Nitrosylases and their substrates

Nitrosylases	Substrates	Reference
Metal-to-Cys
Hemoglobin	Auto-S-nitrosylation	[17, 18]
Cytoglobin^a		[22]
Neuroglobin^a		[22]
Cytochrome c^a	Glutathione	[19]
Ceruloplasmin	Glutathione	[20]
Ceruloplasmin	Glypican-1	[21]
Cys-to-Cys
Hemoglobin	AE1	[27]
Hemoglobin	Glutathione	[30]
Thioredoxin	Caspase-3	[46–48]
Thioredoxin	~ 50 proteins	[48]
GAPDH	HDAC	[37]
	SIRT-1	[37]
	DNA-PK	[37]
Caspase-3	Thioredoxin	[50]
Caspase-3	X-linked inhibitor of apoptosis	[40]
Cyclin-dependent kinase 5	Dynamin-related protein 1	[44]

Indicates in vitro reaction of unknown physiological relevance