Table 2.

Gene ontology processes associated with the androgen candidate gene set identified by androgen candidate gene ontology identified using Metacore

Processes	Target	P value	Z-score
Regulation of biological quality (57.5%), regulation of apoptosis (42.5%), regulation of programmed cell death (42.5%)	14	5.74e-43	119.50
Regulation of biological quality (54.5%), embryonic placenta development (13.6%), oxygen homeostasis (9.1%)	6	2.18e-16	61.16
Regulation of ion transport (27.0%), positive regulation of hydrolase activity (32.4%), positive regulation of phospholipase activity (24.3%)	4	5.94e-10	35.52

Note that the term target indicates the number of candidate genes/proteins/compounds (objects) in a data set that are associated with a given network/process. The P value (the probability of a random intersection) indicates a measure of relevance of the intersection between a gene/protein and an entity in a particular ontology. The lower the P value, the higher is the nonrandomness of finding such intersection. The Z-score ranks the networks with regard to the number of objects present in the networks. The higher the Z-score, the higher the number of objects from the data set.