Fig. 1.

Functional connectivity analysis. Patients with posttraumatic stress disorder (PTSD; C) compared with combat controls (CC; B) showed reduced anticorrelation between the left amygdala (seed region shown in A) and the rostral anterior cingulate cortex (D top), increased positive connectivity between the left amygdala and right insula (D middle) and reduced positive connectivity between the right amygdala and left hippocampus (D bottom). Slices displayed at Montreal Neurological Institute coordinates x = 3 (top row), z = 1 (middle row) and y = −18 (bottom row). Activations are corrected for multiple comparisons within regions of interest.