Table 4.
Top left-right atria differentially regulated genesets by presence of conserved miRNA motif in the 3' UTR of atrial expressed genes.
| Motif | Right* | Left* | Hypothesis |
|---|---|---|---|
| CACTGCC,MIR-34A,MIR-34C,MIR-449 | 20 | 13 | Right |
| GGGACCA,MIR-133A,MIR-133B | 11 | 1 | Right |
| ATGCTGC,MIR-103,MIR-107 | 18 | 7 | Right |
| AGGGCCA,MIR-328 | 8 | 1 | Right |
| CTGAGCC,MIR-24 | 17 | 7 | Right |
| CCTGTGA,MIR-513 | 11 | 5 | Right |
| GGCAGCT,MIR-22 | 24 | 13 | Right |
| CCTGCTG,MIR-214 | 19 | 3 | Right |
| GACAGGG,MIR-339 | 8 | 2 | Right |
| GAGCCAG,MIR-149 | 16 | 5 | Right |
| CCCAGAG,MIR-326 | 12 | 1 | Right |
| GCAAGGA,MIR-502 | 10 | 3 | Right |
| CAGTCAC,MIR-134 | 8 | 0 | Right |
| TCCAGAG,MIR-518C | 14 | 4 | Right |
| CACCAGC,MIR-138 | 17 | 5 | Right |
| CAGCCTC,MIR-485-5P | 16 | 3 | Right |
| CCATCCA,MIR-432 | 4 | 6 | Left |
Genesets were filtered to include only those that contained at least 5 that were significantly up regulated in the right or left atria, and by having the minimum p-value (10−4) under the model-free hypothesis.
*
Number of genes from the geneset that are contained within those found to be expressed higher in the left or right atria via the edgeR analysis (FDR < 0.05).