Skip to main content
. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: JPEN J Parenter Enteral Nutr. 2011 Oct 30;36(4):431–441. doi: 10.1177/0148607111414580

Figure 2. Liver histology and degree of hepatic steatosis after 19 days.

Figure 2

Hematoxylin and eosin stained liver sections of mice with different lipid supplementation. Liver sections from control mice showed normal hepatic architecture (A). HCD-only livers exhibited diffuse macro- and microvesicular steatosis in the periportal and midzone hepatocytes (B). HCD-0 livers were similar to HCD-only livers (C). HCD-0.21 livers showed a moderate reduction of steatosis in the periportal and midzone regions (D). HCD-2.1 and HCD-4.2 livers had well-preserved hepatic architecture with no focal microvacuoles (E–F). The results were reflected in the steatosis scores of these groups (G) in which mice in the HCD-only, HCD-0 and HCD-0.21 groups had higher median scores than control animals (*P<0.05). Data are expressed as median ± IQR. Group medians were compared using the Kruskal-Wallis test.