. Author manuscript; available in PMC: 2013 Jun 20.

Published in final edited form as: J Am Chem Soc. 2012 Jun 6;134(24):9898–9901. doi: 10.1021/ja303446w

Table 1.

Diameter of growth inhibition zones (mm) in the agar diffusion antibacterial susceptibility assay.

	10^a		11		Ampicillin		Amoxicillin

	+Fe	−Fe	+Fe	−Fe	+Fe	−Fe	+Fe	−Fe
P. aeruginosa KW799/wt	20	24	25	26		23p	27	18p
P. aeruginosa KW799/61	13P	21	13P	26	40	40	42	39
P. aeruginosa PAO1	0	16	0	19	0	0	0	0
P. aeruginosa Pa4	0	18	0	20	0	h	0	h
P. aeruginosa Pa6	0	0	0	0	0	0	0	0
P. aeruginosa K648 (pvd−, pch–)	0	15	0	17	0	0	0	0
E. coli H1443 (fepA+, cir+, fiu+)	0	19	0	21	19/23P	16/23p	19/24P	19/23p
E. coliH 1876 (fepA−, cir−, fiu−)	0	0	0	14P	0	0	0	0

p, partially clear inhibition zone/colonies in the inhibition zone; P, unclear inhibition zone/many colonies in the inhibition zone; h: indicates only a hint of growth inhibition detectable; Exactly 50 μL of a 0.2 mM solution of each compound dissolved in 1:9 DMSO/MeOH was added to 9 mm wells in agar media (Standard I Nutrient Agar, Serva or Mueller Hinton II Agar, Becton, Dickinson and Company); Inhibition zones were read after incubation at 3 7 °C for 24 h.

Compound 10 was tested at 0.1 mM.