Table 6.

Relationship between CYP4A11 T8590C and components of the metabolic syndrome in the Vanderbilt BioVU Cohort

	Obesity	Hypertriglyceridemia	High Blood Pressure	Impaired Fasting Glucose	Low HDL-C	Metabolic Syndrome
Unadjusted P
All (N=708)	0.31	0.54	0.83	0.28	0.14	0.92
Female (N=360)	0.32	0.75	0.93	0.12	0.03	0.53
Male (N=348)	0.67	0.73	0.58	0.82	0.97	0.37
Adjusted P*
All (708)		0.56	0.91	0.25	0.15	0.83
Female (N=360)		0.91	0.90	0.06	0.04	0.76
Male (N=348)		0.61	0.69	0.96	0.96	0.48

^*Adjusted for age, age² and body mass index. Subjects taking estrogen were excluded. HDL-C indicates high density lipid cholesterol