Table 2.
Resting Electrocardiographic and Echocardiographic Parameters by Median TpTe Interval
| Parameter | All patients (N=84) |
TpTe < 75 ms (N=41) |
TpTe ≥ 75 ms (N=43) |
P value |
|---|---|---|---|---|
| T peak – T end interval (ms) | 75±17 | 61±8 | 88±11 | |
| Electrocardiography: | ||||
| PR interval (ms) | 160±28 | 153±23 | 167±31 | 0.03 |
| QRS interval (ms) | 90±14 | 87±9 | 93±17 | 0.06 |
| QT interval (ms) | 401±41 | 390±30 | 413±46 | 0.01 |
| QTc interval (ms) | 423±27 | 416±22 | 430±29 | 0.02 |
| QRS axis (degrees) | 36±38 | 46±29 | 27±42 | 0.02 |
| Echocardiography: | ||||
| LV end-diastolic dimension (cm) | 4.4±0.6 | 4.3±0.6 | 4.4±0.5 | 0.69 |
| LV end-systolic dimension (cm) | 2.9±0.5 | 2.9±0.5 | 2.9±0.5 | 0.91 |
| LV posterior wall thickness (cm) | 1.0±0.2 | 0.9±0.1 | 1.0±0.2 | 0.02 |
| LV septal wall thickness (cm) | 1.0±0.2 | 0.9±0.1 | 1.0±0.2 | 0.02 |
| LV mass index (g/m2) | 78±20 | 75±20 | 80±20 | 0.22 |
| LV ejection fraction (%) | 60±4 | 59±3 | 60±5 | 0.24 |
| Left atrial dimension (cm) | 3.3±0.4 | 3.2±0.5 | 3.4±0.4 | 0.12 |
| Early mitral inflow (E) velocity (cm/s) | 83±19 | 88±20 | 80±17 | 0.04 |
| Late mitral inflow (A) velocity (cm/s) | 69±17 | 67±17 | 70±16 | 0.44 |
| E/A ratio | 1.3±0.5 | 1.4±0.6 | 1.2±0.3 | 0.03 |
| Mitral E deceleration time (ms) | 204±70 | 198±70 | 210±71 | 0.42 |
| Septal e' tissue velocity (cm/s) | 9.3±2.8 | 10.9±2.3 | 7.7±2.2 | <0.0001* |
| E/e' ratio | 9.5±3.0 | 8.3±2.2 | 10.7±3.2 | 0.0001* |
| Diastolic function (n, %) | <0.0001* | |||
| Normal diastolic function | 53 (63) | 40 (98) | 13 (30) | |
| Grade 1 diastolic dysfunction | 11(13) | 1(2) | 10 (23) | |
| Grade 2 or 3 diastolic dysfunction | 20 (24) | 0 (0) | 20 (47) | |
*
Remains significant after correction for multiple comparisons