Table 4.
Genes that increased in livers of iron-deficient rats compared to pair-fed rats
| Gene name | Gene symbol | Fold regulation | P value |
|---|---|---|---|
| Insulin signaling array | |||
| Insulin1 | Ins1 | +11.8 | 0.026 |
| Fatty acid synthase | Fasn | +9.2 | 0.052 |
| Insulin2 | Ins2 | +8.4 | 0.006 |
| Glucose-6-phosphatase, catalytic subunit | G6pc | +4.0 | 0.008 |
| Sterol regulatory element binding transcription factor 1 | Srebf1 | +2.9 | 0.082 |
| Low density lipoprotein receptor | Ldlr | +2.9 | 0.012 |
| Nitric oxide synthase 2, inducible | Nos2 | +2.1 | 0.037 |
| Acetyl-Coenzyme A carboxylase alpha | Acaca | +2.1 | 0.034 |
| Neuropeptide Y | Npy | +1.8 | 0.047 |
| V-akt murine thymoma viral oncogene homolog 2 | Akt2 | +1.5 | 0.017 |
| Glycogen Synthase kinase 3 beta | Gsk3b | +1.5 | 0.016 |
| Bcl2-like 1 | Bcl2l1 | +1.5 | <0.001 |
| Glucose metabolism array | |||
| Amylo-1,6-glucosidase, 4-alpha-glucanotransferase | Agl | +5.9 | 0.035 |
| Phosphorylase, glycogen, liver | Pygl | +5.0 | 0.001 |
| Pyruvate dehydrogenase kinase, isozyme 1 | Pdk1 | +4.8 | 0.053 |
| ATP citrate lyase | Acly | +4.7 | 0.005 |
| Phosphoglycerate kinase 1 | Pgk1 | +4.0 | <0.001 |
| Glyceraldehyde-3-phosphate dehydrogenase | Gapdh | +3.3 | 0.038 |
| Pyruvate kinase, liver and RBC | Pklr | +3.1 | 0.005 |
| Glucose-6-phosphate dehydrogenase | G6pd | +2.5 | 0.014 |
| Transkeletose | Tkt | +2.4 | <0.001 |
| Ribokinase | Rbks | +2.2 | 0.050 |
| Pyruvate dehydrogenase kinase, isozyme 4 | Pdk4 | +2.1 | 0.008 |
| Pyruvate dehydrogenase (lipoamide) beta | Pdhb | +1.9 | 0.035 |
| Phosphofructokinase, liver | Pfkl | +1.8 | 0.004 |
| Dihydrolipoamide dehydrogenase | Dld | +1.8 | 0.039 |
| Transaldolase 1 | Taldo1 | +1.6 | 0.027 |
Fold regulation indicates relative fold change in mRNA abundance in the ID group compared to the PF group