Table 7.
Genes that decreased in gastrocnemius muscles of iron-deficient rats compared to pair-fed rats
| Gene name | Gene symbol | Fold regulation | P value |
|---|---|---|---|
| Insulin signaling array | |||
| Fructose-1,6- biphosphatase 1 | Fbp1 | −2.1 | 0.013 |
| Eukaryotic translation initiation factor 4E binding protein 1 | Eif4ebp1 | −1.9 | 0.006 |
| Bcl2-like 1 | Bcl2l1 | −1.9 | 0.000 |
| Insulin Receptor | Insr | −1.8 | 0.018 |
| V-akt murine thymoma viral oncogene homolog 1 | Akt1 | −1.5 | 0.049 |
| Glucose metabolism array | |||
| Pyruvate dehydrogenase kinase, isozyme 4 | Pdk4 | −4.4 | 0.021 |
| Hexokinase 3, white cell | Hk3 | −3.1 | 0.012 |
| Frucotse = 6,6-bisphosphatase 2 | Fbp2 | −2.9 | 0.010 |
| Enolase 3, beta, muscle | Eno3 | −2.3 | 0.008 |
| Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | H6pd | −2.2 | 0.036 |
| Glucose 6 phosphatase, catalytic, 3 | G6pc3 | −2.2 | 0.024 |
| Enolase 2, gamma, neuronal | Eno2 | −2.2 | 0.0499 |
| Phosphoglycerate mutase 2 (muscle) | Pgam2 | −2.1 | 0.019 |
| Galactose mutarotase (aldose 1-epimerase) | Galm | −2.1 | 0.002 |
| Phosphoenolpyruvate carboxykinase 2 | Pck2 | −2.1 | 0.012 |
| Glycogen synthase 1, muscle | Gys1 | −2.2 | 0.051 |
| Succinate-CoA ligase, GDP-forming, beta subunit | Suclg2 | −2.0 | 0.017 |
| Oxoglutarate dehydrogenase-like | Ogdhl | −1.9 | 0.037 |
| Transaldolase 1 | Taldo1 | −1.9 | 0.025 |
| Glycogen synthase kinase 3 alpha | Gsk3a | −1.7 | 0.031 |
| Glycogen synthase kinase 3 beta | Gsk3b | −1.7 | 0.029 |
| Isocitrate dehydrogenase 2 (NADP +), mitochondrial | Idh2 | −1.6 | 0.014 |
| Aconitase 2, mitochondrial | Aco2 | −1.6 | 0.012 |
| Isocitrate dehydrogenase 3 (NAD +) beta | Idh3b | −1.5 | 0.046 |
| Fatty acid metabolism array | |||
| Carnitine palmitoyltransferase 1a, liver | Cpt1a | −8.1 | 0.000 |
| Carnitine palmitoyltransferase 2 | Cpt2 | −4.4 | 0.000 |
| 3-hydroxybutyrate dehydrogenase, type 2 | Bdh2 | −2.9 | 0.000 |
| 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) | Hmgcs2 | −2.8 | 0.000 |
| Solute carrier family 27 (fatty acid transporter), member 2 | Slc27a2 | −2.5 | 0.000 |
| Acyl-CoA thioesterase 12 | Acot12 | −2.3 | 0.005 |
| 2,4-dienoyl CoA reductase 1, mitochondrial | Decr1 | −2.2 | 0.000 |
| Acyl-CoA thioesterase 2 | Acot2 | −2.2 | 0.003 |
| Acyl-Coenzyme A dehydrogenase family, member 11 | Acad11 | −2.2 | 0.003 |
| Acetyl-Coenzyme A acyltransferase 2 | Acaa2 | −1.9 | 0.002 |
| Hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | Hadha | −1.9 | 0.002 |
| Carnitine acetyltransferase | Crat | −1.7 | 0.009 |
| Glycerol-3-phosphate dehydrogenase 2, mitochondrial | Gpd2 | −1.7 | 0.006 |
| Acyl-Coenzyme A oxidase 3, pristanoyl | Acox3 | −1.6 | 0.015 |
| Acyl-Coenzyme A dehydrogenase family, member 10 | Acad10 | −1.5 | 0.008 |
| Solute carrier family 27 (fatty acid transporter), member 4 | Slc27a4 | −1.5 | 0.002 |
Fold regulation indicates relative fold change in mRNA abundance in the ID group compared to the PF group