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. 2012 Apr 27;31(12):2755–2769. doi: 10.1038/emboj.2012.110

Figure 7.

Figure 7

Homologues of metazoan germ granule-associated genes are upregulated in neoblasts. (A, B) Average transcript (A) and protein (B) fold changes between X1 and Xins for homologues of metazoan germ granule-associated RNA-binding proteins (RBPs). The number of metazoan genes with planarian homologues and measured fold changes is shown in parentheses. Error bars represent the standard error of the mean. Enrichment of upregulated genes (P) was assessed by Fisher’s exact test. (C) ISH in wild type (WT) versus irradiated (IRR) animals reveals neoblast expression of four genes homologous to granule components (MOV10L1a, MOV10L1b, TDRD9, and DAZL). Asterisks mark midline posterior to the pharynx where neoblasts are concentrated. Scale bars are 0.5 mm in (C).