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Wnts regulate neuronal polarity. In C. elegans, ALM neuronal polarity is shaped by the Wnts CWN-1 and EGL-20 and the Ror receptor CAM-1, whereas PLM neuronal polarity is shaped by the Wnt LIN-44 and the Fz receptor LIN-17. Note that the Wnt (LIN-44, CWN-1, EGL-20) gradients high in posterior and low in anterior.
