Figure 4.

Pulmonary compliance measurements in WT and CC chemokine receptor (CCR) 2 knockout (CCR^−/−) mice after LC. “Quasistatic” closed-chest pressure–volume behavior was measured at 5, 24, 48, and 72 hours after injury in WT and CCR2^−/− mice. Points along each curve represent the mean (±SEM) for nine animals at each time point. Each experiment was repeated at least three times with three animals per group. Asterisks represent a significant difference between the groups described in each graph (see main text for details).