Table 1.
Correlations between the co-expression of wild-type KIT receptor and stem cell factor and clinicopathological factors in gastrointestinal stromal tumors
|
Co-expression of wild-type KIT receptor and stem cell factor |
|||
| Absent (n = 12) | Present (n = 39) | P value | |
| Age (yr) | 58.9 ± 13.2 | 52.8 ± 10.5 | 0.0524 |
| Sex | |||
| Male | 6 | 18 | 0.8154 |
| Female | 6 | 21 | |
| Tumor size (cm) | 3.69 ± 1.68 | 6.21 ± 3.94 | 0.0118 |
| Histological phenotype | |||
| Spindle type | 8 | 26 | 0.7262 |
| Epithelioid/mixed type | 4 | 13 | |
| Cellularity | |||
| Sparse | 1 | 6 | 0.8000 |
| Moderate/dense | 11 | 33 | |
| Tumor location | |||
| Gastric | 6 | 25 | 0.5931 |
| Non-gastric | 6 | 14 | |
| Proliferative index | 2.92 ± 2.23 | 7.21 ± 4.93 | 0.0012 |
| pHH3 | |||
| ≤ 5 | 12 | 24 | 0.0282 |
| > 5 | 0 | 15 | |
| Mitotic counts | 3 ± 2.37 | 7.36 ± 6.36 | 0.0058 |
| ≤ 5 | 10 | 14 | 0.0004 |
| > 5 | 2 | 25 | |
| Apoptosis index | 44.58 ± 19.00 | 32.59 ± 17.63 | 0.0484 |
| c-kit mutation | |||
| Presence | 5 | 27 | 0.1659 |
| Absence | 7 | 12 | |
| National Institutes of Health risk group | |||
| Very low or low | 10 | 10 | 0.0012 |
| Intermediate or high | 2 | 29 | |