Table 1.
Basic clinical characteristics of patients with hepatitis B virus-related hepatocellular carcinoma (n = 354)
Clinical features | Stage A | Stage B | Stage C |
Cases (n) | 138 | 96 | 120 |
Median age (yr, range) | 55 (24-68) | 53 (29-70) | 52 (21-72) |
Male/female | 118/20 | 82/14 | 106/14 |
Median tumor diameter (cm, range) | 2.5 (1.5-3) | 4.0 (3-5) | 4.5 (2-6) |
AFP (μg/L, > 400/≤ 400) | 45/93 | 40/56 | 85/35 |
HBV DNA (+/-) | 78/60 | 57/39 | 76/44 |
HBeAg (+/-) | 50/88 | 32/64 | 54/66 |
ECOG PS (0/1/2) | 92/30/16 | 60/25/11 | 25/55/40 |
Child-Pugh (A/B) | 92/46 | 67/29 | 58/62 |
Tumor number (single/multinodular) | 123/15 | 56/40 | 67/53 |
Invasion of portal vein (+/-) | 0/138 | 0/96 | 120/0 |
Tumor differentiation (high/intermediate/low) | 45/66/27 | 27/38/31 | 20/50/50 |
HBV: Hepatitis B virus; ECOG PS: Eastern Cooperative Oncology Group Performance Status Scale; AFP: α- fetoprotein; HBeAg: HBV e antigen.