Figure 2.

Although the BG1 mice have a reduced population of CD4 T cells, the FoxP3-GFP⁺ cells in BG1x Foxp3-DTR/GFP mice are concentrated in the CD4 population. (A) Comparison of Foxp3-GFP⁺ T cells in PBL from mice with and without the TCR transgenes. (B) Association of the Foxp3-GFP⁺ Tregs with the Vβ7⁺ CD4 and CD8 T cells. The distribution of Tregs in the Vβ7⁺ populations of T cells from peripheral blood was unaffected by retinal βgal expression. Analyses were gated on CD3⁺ T cells. Representative plots are shown.