Skip to main content
. Author manuscript; available in PMC: 2012 Jun 21.
Published in final edited form as: J Neurosurg. 2010 Oct;113(4):802–809. doi: 10.3171/2009.10.JNS09562

Fig. 1.

Fig. 1

Effect of TSC on cerebral infarct volume in a model of permanent (24-hour) focal ischemia. The bar graph shows group means and SEs for the vehicle- and TSC-treated animals (7 rats per group). The volume of cerebral infarction was reduced by TSC in a dose-dependent manner, characterized by a U-shaped curve. This protective action achieved statistical significance at TSC dosages ranging from 0.023 to 0.229 mg/kg, with a maximal protective effect being achieved at 0.092 mg/kg. * p < 0.05, 1-way ANOVA and the LSD post hoc test.