TABLE 1.

Physiological parameters in animals from the permanent (24-hour) ischemia experiment (Experiment 1)^*

Dosage & Timing of Measurements	MABP (mm Hg)	HR (beats/min)	pH	PCO2 (mm Hg)	PO2 (mm Hg)
vehicle
before 3-VO	122.9 ± 4.2	353.4 ± 8.8	7.453 ± 0.020	29.1 ± 2.8	168.0 ± 12.3
during 3-VO & infusion	122.8 ± 2.8	377.2 ± 11.4	7.446 ± 0.022	29.2 ± 2.5	175.8 ± 10.6
after infusion	125.8 ± 2.2	385.5 ± 6.5	7.427 ± 0.026	31.3 ± 2.2	176.1 ± 9.2
0.023 mg/kg TSC
before 3-VO	121.1 ± 3.7	376.6 ± 7.2	7.470 ± 0.019	28.2 ± 1.8	178.6 ± 8.1
during 3-VO & infusion	119.6 ± 4.0	394.7 ± 10.8	7.474 ± 0.011	31.9 ± 0.7	178.5 ± 7.9
after infusion	124.0 ± 5.1	392.2 ± 10.2	7.458 ± 0.018	28.5 ± 2.0	179.3 ± 9.4
0.046 mg/kg TSC
before 3-VO	121.6 ± 3.2	369.1 ± 5.6	7.455 ± 0.016	32.0 ± 2.6	190.2 ± 7.1
during 3-VO & infusion	123.6 ± 3.4	386.3 ± 12.5	7.457 ± 0.017	31.2 ± 2.3	176.8 ± 6.3
after infusion	119.5 ± 1.7	377.3 ± 14.4	7.460 ± 0.017	32.1 ± 2.8	168.6 ± 7.5
0.092 mg/kg TSC
before 3-VO	125.0 ± 6.8	364.6 ± 8.0	7.480 ± 0.015	31.5 ± 2.6	192.5 ± 7.0
during 3-VO & infusion	124.4 ± 4.1	386.4 ± 13.9	7.451 ± 0.016	30.6 ± 1.5	183.3 ± 6.8
after infusion	122.8 ± 3.3	376.4 ± 15.8	7.426 ± 0.007	33.8 ± 1.6	168.2 ± 8.8
0.230 mg/kg TSC
before 3-VO	116.3 ± 5.4	378.3 ± 9.8	7.474 ± 0.013	30.3 ± 1.5	185.7 ± 9.8
during 3-VO & infusion	121.8 ± 4.3	394.7 ± 4.0	7.461 ± 0.017	30.2 ± 1.5	190.6 ± 9.8
after infusion	131.3 ± 6.3	397.5 ± 12.1	7.453 ± 0.016	30.4 ± 2.3	187.6 ± 6.4
0.458 mg/kg TSC
before 3-VO	117.5 ± 3.4	339.7 ± 17.6	7.457 ± 0.014	30.5 ± 2.1	167.5 ± 12.0
during 3-VO & infusion	128.5 ± 6.7	357.3 ± 18.7	7.433 ± 0.020	29.4 ± 2.6	171.9 ± 11.4
after infusion	125.2 ± 6.2	355.2 ± 5.9	7.436 ± 0.006	29.7 ± 1.9	174.4 ± 11.2
0.916 mg/kg TSC
before 3VO	113.7 ± 4.4	347.3 ± 6.7	7.432 ± 0.012	31.4 ± 2.3	177.1 ± 7.7
during 3-VO & infusion	115.9 ± 4.0	370.1 ± 10.5	7.447 ± 0.015	32.2 ± 1.7	182.2 ± 6.8
after infusion	110.7 ± 2.3	364.9 ± 7.1	7.444 ± 0.012	31.6 ± 1.5	184.8 ± 4.9
2.290 mg/kg TSC
before 3-VO	118.8 ± 6.7	347.2 ± 7.9	7.451 ± 0.021	31.7 ± 1.8	177.4 ± 6.3
during 3-VO & infusion	119.6 ± 5.3	359.8 ± 8.6	7.435 ± 0.007	32.0 ± 2.2	178.2 ± 4.5
after infusion	116.8 ± 4.7	356.4 ± 9.1	7.439 ± 0.005	31.6 ± 1.6	182.8 ± 4.6
4.580 mg/kg TSC
before 3-VO	110.7 ± 2.7	357.0 ± 12.3	7.452 ± 0.017	27.6 ± 2.6	178.8 ± 8.2
during 3-VO & infusion	113.1 ± 2.5	374.3 ± 11.1	7.456 ± 0.015	30.6 ± 2.0	175.4 ± 6.7
after infusion	111.1 ± 2.3	362.4 ± 12.0	7.443 ± 0.013	31.6 ± 2.5	179.9 ± 4.8

^*Values shown are means ± SEs. No significant intergroup differences were observed for MABP, heart rate, blood pH, blood PCO₂, or blood PO₂.

Abbreviations: HR = heart rate; pH = blood pH; PCO₂ = blood PCO₂; PO₂ = blood PO₂.