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. Author manuscript; available in PMC: 2012 Jun 21.
Published in final edited form as: Antioxid Redox Signal. 2011 Mar 28;14(12):2337–2346. doi: 10.1089/ars.2010.3640

Figure 6. Carbamylated HDL induces SR-BI dependent lipid droplet formation.

Figure 6

(A) SR-BI or LacZ (control) expression was induced in THP-1 macrophages by infection with adenoviral vectors encoding SR-BI or LacZ. Cell surface expression of SR-BI was visualized by immunofluorescence staining with an anti-SR-BI antibody of non-permeabilized cells. (B) SR-BI and LacZ expressing macrophages were incubated with 200 μg/ml native HDL (control) or carbamylated HDL (0.57 or 5.25 HCit/apoA-I) for 48 h at 37°C. The intracellular uptake of neutral lipid was visualized by Bodipy staining.