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. 2012 May 9;3(4):462–474. doi: 10.18632/oncotarget.497

Figure 2. A non-monotonic relationship between gene-body DNA methylation and gene expression.

Figure 2

Overall percentage methylation of gene-bodies (regions starting at 1kb downstream of the TSS and ending at 1kb upstream of the TTS of genes) is regressed against gene expression for (A) GM12878 (B) K562 and (C) HepG2. Genes are grouped into 100 gene expression bins.