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. Author manuscript; available in PMC: 2012 Jun 21.
Published in final edited form as: Hypertension. 2010 Mar 29;55(5):1246–1253. doi: 10.1161/HYPERTENSIONAHA.110.150540

Figure 2. TNF-α blockade reduces AT1-AA-induced preeclamptic-like features.

Figure 2

The key features of PE, hypertension (A) and proteinuria (B) present in the PE-IgG-injected pregnant mice were reduced by co-injection with a TNF-α blocker. In addition, sFlt-1 (C) and sEng (D) were also reduced with the co-injection of the autoantibody and the TNF-α blocker. n=9 for each variable. *P<0.05 versus NT-IgG. **P<0.05 versus PE-IgG.