Table I.

Clinical characteristics of the study population

	NO FIRS (n=108)	FIRS (n=44)	p
Age (years)	24.3 (15–38)	24.5 (15–39)	0.8
GA at cordocentesis (weeks)	30.7 (18.2–35.5)	29.2 (20–36)	0.02
Preterm PROM	29 (26.9%)	21 (47.7%)	0.01
Intra-amniotic infection	14 (13%)	27 (61.4%)	<0.001
Clinical chorioamnionitis	6 (5.6%)	10 (62.5%)	0.002
Antenatal steroids prior to cordocentesis	29 (26.9%)	13 (29.5%)	0.7
Tocolysis prior to cordocentesis	71 (65.7%)	23 (52.3%)	0.1
Antibiotics prior to cordocentesis	27 (25%)	13 (30.2%)	0.5
Preterm delivery	79 (73.1%)	42 (95.5%)	0.002
Delivery within 72 hours	22 (20.4%)	35 (79.5%)	<0.001
GA at delivery (weeks)	34.3 (24–41.8)	30.1 (20–38.3)	<0.001
Interval to delivery (hours)	608.2 (2–3384)	149.7 (1–1368)	<0.001
Birthweight (grams)	2327 (490–4337)	1568 (360–3480)	<0.001
Fetal blood IL-6 (pg/mL)	4.8 (0.3–10.8)	171.6 (11.5–900)	<0.001

Values were expressed as number (percent) or median (range)

FIRS: Fetal inflammatory response syndrome

GA: Gestational age; PROM: prelabor rupture of membranes