Table 2.

Patients not surviving after allogeneic transplantation for LAD

	Donor	Age (months)	Year BMT	Conditioning	Graft	GVHD Prophylaxis	GVHD Grade	Engraftment	Cause of death
1	MSD	15	1995	BU VP16	BM	Mtx		Yes	Pneumonitis
2	MSD	3	2001	BU CY	BM	CyA		Yes	VOD
3	MSD	8	2001	BU CY	BM	CyA Mtx Pred		Yes	VOD
4	MUD	168	1996	BU CY Cam1G	BM	CyA Mtx		Yes	Infection
5	MUD MUD	13	1998	BU CY ATG BU CY VP16 ATG	BM BM	CyA Mtx	II	Yes	Infection
6	HAPL MUD	19	1993	BU CY VP16 TBI CY ATG	BM T dep BM	CyA	I	No	Infection, Malignancy
7	HAPL(P) HAPL(M)	5	1994	BU CY VP16 αLFA-1 αCD2 BU CY VP16 Cam1G	BM T dep BM T dep			Yes	Infection VOD
8	HAPL(P) HAPL(M) HAPL(M)	3	1997	BU CY αCD2 BU CY αCD2 ATG CY ATG	BM T dep BM T dep BM T dep	CyA		Yes	Infection
9	HAPL(M) HAPL(P)	4	2004	BU CY ATG BU CY ATG	BM T dep PBSC/CD34			No	ARDS

^*Indicates Reduced Intensity Conditioning (RIC). Other abbreviations for Tables 1 & 2: ARA-C, Cytarabine; ARDS, Acute respiratory distress syndrome; ATG, Antithymocyte gobulin; BM, Bone Marrow; Bu, Busulphan; Cam1G, Campath 1G; Cam1H, Campath 1H; CMV, Cytomegalovirus; CY Cyclophosphamide; CyA, Cyclosporin; EBV, Epstein Barr Virus; HAPL, Haloidentical donor (P-paternal, M-maternal); MFD, Matched family donor; MSD, Matched sibling donor; MUD, Matched unrelated donor; MMUD, Mismatched unrelated donor (1-3 antigens); PBSC, Peripheral blood stem cell collection (CD34 selected where indicated); MNC, mononuclear cells; Mtx, Methotrexate; MMF, Mycophenolate mofetil; PMN, Polymorphonuclear cells; Prd, prednisolone; T dep, T cell depleted; TP, Thiopeta; UCB, Umbilical cord blood; VP16, Etoposide; VOD, Veno-occlusive disease; VZV, Varicella zoster virus