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. 2012 Mar 15;5(4):492–502. doi: 10.1242/dmm.008730

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© 2012. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms

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Fig. 6. — Induction of apoptosis after myc17 activation in vivo. (A) Detection of apoptosis by TUNEL assays in liver and gill sections from adult fish. Fish were treated for 24 hours with 4-OHT. DNA fragmentation is visible as red spots colocalizing with nuclei, which are stained with Hoechst. Scale bar: 10 μm. (B) Quantification of the percentage of apoptotic cells in liver (left panel) and gills (right panel) of both myc17ER lines in the presence or absence of 4-OHT. C N indicates total cell number for each assay.