Table 2.
Fucosylated and corresponding non-fucosylated glycan structures associated with HCC and adjacent tissue.
Glycan1 | Tumor Mean (±SD)2 | Non-tumor Mean (±SD)3 | p value |
---|---|---|---|
A2G2 | 37.93 (±4.70) | 38.25(1.95) | >0.05 |
F(6)A2G2 | 14.81 (±5.44) | 13.34 (±3.17) | >0.05 |
A3G3 | 7.06 (±2.42) | 6.40 (±1.74) | >0.05 |
F(6)A3G3 | 3.32 (±1.96) | 2.66 (±1.16) | >0.05 |
A4G4 | 2.87 (±1.03) | 1.55 (±0.65) | 0.0003 |
F(6)A4G4 | 1.76 (±0.84) | 1.49 (±0.65) | >0.05 |
Key glycans identified in HCC and adjacent tissue. A2G2, bi-antennary glycan; F(6) A2G2, core fucosylated bi-antennary glycan; A3G3, tri-antennary glycan; F(6)A3G3, core fucosylated tri-antennary glycan, A4G4, tetra-antennary glycan; F(6)A4G4, core fucosylated tetra-antennary glycan.
The mean percentage of each glycan in the total glycan profile of the tumor tissue.
The mean percentage of each glycan in the total glycan profile of the adjacent (non tumor) tissue.