Table 1.

Comparison of CAM concentrations used in cell line/xenograft and human studies

Data for several common CAM therapies used by prostate cancer patients have been converted to micromolar (μM) units and microgram per milliliter (μg/mL) concentrations. Achievable human concentrations are shown as μM and μg/mL to facilitate comparison.

Abbreviations: AR, androgen receptor; Bcl-2, B-cell lymphoma 2; CAM, complementary and alternative medicine; EGCG, epigallocatechin 3-gallate; FOXO, forkhead box O; IGF, insulin-like growth factor; mTOR, mammalian target of rapamycin; NF, nuclear factor; PI3K, phosphoinositol-3-kinase; PSA, prostate-specific antigen; VEGF, vascular endothelial growth factor.